منابع مشابه
The synergistic effect of gentamicin and clindamycin on rocuronium-induced neuromuscular blockade
BACKGROUND Gentamicin reduces acetylcholine release and clindamycin causes end-plate ion channel blockade. Because of these reasons, two drugs show muscular relaxant effect and potentiate the action of nondepolarizing neuromuscular agents. This study was intended to evaluate the effect of gentamicin and clindamycin on rocuronium-induced neuromuscular blockade and the interaction between these d...
متن کاملNeuromuscular blockade in children.
Neuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and a...
متن کاملMonitoring neuromuscular blockade.
Neuromuscular-blocking agents (NMBA) have been used in clinical anesthesia for nearly 60 years. In the perioperative period, a variety of factors can influence a patient’s response to these drugs. To precisely titrate NMBAs to clinical effects in the anesthetized patient, the application of neuromuscular monitoring is essential. The use of a peripheral nerve stimulator allows the clinician to a...
متن کاملHyperkalemia-induced residual neuromuscular blockade: a case report.
Muscle relaxants are routinely administered during anesthesia. The residual effects of nondepolarizing muscle relaxants must be reversed by the anesthesia provider prior to extubation of the trachea to ensure that patients can safely protect their own airways and maintain adequate ventilation. Many factors can potentiate the effects of muscle relaxants, and each of these factors must be taken i...
متن کاملEffect of ulinastatin on the rocuronium-induced neuromuscular blockade
BACKGROUND Ulinastatin is a glycoprotein derived from human urine and a serine protease inhibitor found in human urine and blood. Ulinastatin increases both liver blood flow and urine output. Rocuronium is eliminated mainly through the liver and partly through the kidney, hepatic elimination of rocuronium might be enhanced by ulinastatin. We examined the effect of ulinastatin on the neuromuscul...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1995
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03011880